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Its use has surged since the Food and Drug Administration (FDA) As a result, the idea of using a compounded version of semaglutide thats mixed with other drugs or different ingredients has become more popular

Another factor is the amount of receptors that your small intestine cells have for the B12-IF complex which is largely determined by your genes

In rare cases, Saxenda can cause more serious side effects, such as pancreatitis (inflammation of the pancreas), gallbladder problems, and kidney problems

If a GLP-1 medication slows digestion, slows gastric emptying, or reduces appetite, edible effects may feel less predictable

These data were first presented by Amanda Johnson, MD, Mayo Clinic, Rochester, Minnesota, at the 2026 Crohns and Colitis Congress on Friday, January 23, 2026, in Las Vegas, Nevada